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Mitosis

Rigorous, lab-informed study of mitosis from cell-cycle control to spindle mechanics and quantitative experimental analysis.

Science · Advanced

Free · Self-paced · Certificate included

Mitosis

About this course

This course provides a rigorous, lab-informed exploration of mitosis from foundational concepts to modern experimental and analytical methods. Starting with the role of cell division in development and homeostasis, it proceeds through cell-cycle control, chromosomal mechanics, and phase-by-phase events with emphasis on fidelity mechanisms. Learners connect structure to function in spindles and kin...

What you'll learn

  • Explain cell-cycle architecture and checkpoint control that govern mitotic entry and fidelity
  • Describe phase-by-phase mitotic events and the mechanics of spindles, kinetochores, and microtubules
  • Analyze forces and molecular mechanisms driving chromosome alignment and segregation
  • Interpret experimental data from microscopy, live-cell imaging, and quantitative assays of mitosis
  • Design experiments to measure mitotic dynamics and assess error rates and fidelity mechanisms
  • Apply quantitative image analysis and basic modeling to spindle and kinetochore behavior
  • Assess how mitotic errors contribute to aneuploidy, cancer, and therapeutic strategies
  • Critically evaluate primary literature and translate findings into experimental hypotheses
  • Communicate experimental results and troubleshooting strategies for mitosis studies

Prerequisites

Undergraduate-level cell and molecular biology and basic laboratory experience; familiarity with microscopy and introductory statistics recommended.

Level
Advanced· Level
Duration
8 weeks (approx. 40–60 hours)· Duration
Language
English· Language
Modules
10· Modules

Skills you'll gain

  • Cell-cycle biology
  • Microscopy and live-cell imaging principles
  • Quantitative image analysis
  • Experimental design in mitosis
  • Biophysical modeling of spindle dynamics
  • Data analysis (R/Python/Excel)
  • Critical reading of primary literature
  • Troubleshooting experimental assays
  • Scientific communication and reporting

What you'll study

10 modules — work at your own pace.

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Frequently asked questions

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