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Mitosis
Chapters

1Foundations of Cell Division and Mitosis

2Cell Cycle Architecture and Checkpoints

3Prophase and Prometaphase Mechanics

4Metaphase Alignment and Spindle Dynamics

5Anaphase Segregation and Force Generation

6Telophase and Cytokinesis

7Molecular Control of Mitosis

Cyclin CDK Core EngineCdc25 and Wee1 SwitchesAPC C Cofactors Cdc20 and Cdh1Ubiquitin Proteasome RegulationSpindle Assembly Checkpoint CoreMitotic Checkpoint ComplexAurora Kinase FamilyPolo Like Kinase 1Nek Kinases in MitosisGreatwall PP2A B55 PathwayPhosphatase Targeting and TimingSubstrate Degradation MotifsSpatial Gradients and CompartmentsMitotic Exit Network ConceptsFeedback and Bistability

8Spindle, Kinetochores, and Microtubule Dynamics

9Mitotic Errors, Aneuploidy, and Disease

10Methods and Quantitative Analysis in Mitosis

Courses/Mitosis/Molecular Control of Mitosis

Molecular Control of Mitosis

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Integrates cyclin-CDK engines, APC/C regulation, checkpoints, kinases, and phosphatases into a systems view.

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Cyclin CDK Core Engine

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